Adam Croft

Professor Adam Croft BSc (Hons), MBChB, PhD, MRCP (UK)

Department of Inflammation and Ageing
Head of Department of Inflammation and Ageing
Professor of Translational Rheumatology
Kennedy Trust for Rheumatology Research Senior Clinical Research Fellow, Versus Arthritis Chair of Rheumatology

Contact details

Telephone: +44 (0)121 3713266
Email: a.p.croft@bham.ac.uk
Twitter

Address: Rheumatology Research Group
Department of Inflammation and Ageing
黑料吃瓜网
Queen Elizabeth Hospital, Birmingham, B15 2WB

Adam is Head of Department of Inflammation and Ageing, a multidisciplinary research department of discovery scientists and clinicians, translating mechanisms which underpin inflammation into new treatments/pathways for inflammatory diseases. Adam is also a Professor of Translational Rheumatology and an Honorary Consultant Rheumatologist at Sandwell and West Birmingham Hospitals and University Hospital of Birmingham NHS Trusts. He is also the Versus Arthritis Chair of Rheumatology.

His main research interest is the development of novel immunotherapies for patients with autoimmune rheumatic and chronic inflammatory diseases, with a particular interest in the development of stromal cell (fibroblast) specific targets. He has received funding from the Wellcome Trust and NIHR.

His clinical interests include management of both early and treatment resistant inflammatory arthritis. His research is supported by the Kennedy Trust for Rheumatology Research, Versus Arthritis and Wellcome Trust.

Qualifications

PG Cert Medical education 2018
PG Cert in Clinical Research Methodology 2015
MRCP (UK) 2012
MBChB 2009
PhD 2005
BSc (Hons) 2002

Teaching

Year 2 BMedSci Immunology tutorials

Postgraduate supervision

Dr Croft's main research interest is in the development of novel immunotherapies for patients with autoimmune rheumatic and chronic inflammatory diseases. He has a particular interest in the development of stromal cell specific targets. His clinical interests include management of both early and treatment resistant inflammatory arthritis. He is also interested in the management of rare systemic inflammatory diseases including vasculitis.

PhD opportunites are available within the Rheumatology Research Group

Other activities

Current

2018- Member of Paediatric and adolescent rheumatology network
2018- Member of Scientific Advisory Committee, NIHR Wellcome Trust Clinical Research facility, 黑料吃瓜网
2016- UK country liaison to EMUNET EULAR advisory group (by competitive national appointment)
2016- Member of West Midlands regional vasculitis network

2015-2018 Chair of British Rheumatologists in Training Advisory Group and West Midlands regional representative (by competitive national appointment)
Member of British Society of Rheumatology Council
Member of Joint Specialty Committee at Royal College of Physicians
Member of rheumatology JRCTPB speciality advisory group
Member of Education and training subcommittee
2016-2018 Member of Clinical Care Quality committee, British Society of Rheumatology (trainee representative)
2016-2018 Member of Peer Review working group, British Society of Rheumatology (trainee representative)
2013-2017 Royal college of Physicians Associate Clinical Tutor, Queen Elizabeth Hospital, Birmingham
2012-2014 Associate Clinical Teaching Fellow, Queen Elizabeth Hospital, Birmingham
2009-2013 Advanced Life Support Instructor, Resuscitation Council UK

Publications

Recent publications

Article

Roche Fibroblast Network Consortium 2025, '', Nature Communications, vol. 16, no. 1, 5.

Rauber, S, Mohammadian, H, Schmidkonz, C, Atzinger, A, Soare, A, Treutlein, C, Kemble, S, Mahony, CB, Geisthoff, M, Angeli, MR, Raimondo, MG, Xu, C, Yang, K-T, Lu, L, Labinsky, H, Saad, MSA, Gwellem, CA, Chang, J, Huang, K, Kampylafka, E, Knitza, J, Bilyy, R, Distler, JHW, Hanlon, MM, Fearon, U, Veale, DJ, Roemer, FW, B盲uerle, T, Maric, HM, Maschauer, S, Ekici, AB, Buckley, CD, Croft, AP, Kuwert, T, Prante, O, Ca帽ete, JD, Schett, G & Ramming, A 2024, '', Nature Immunology.

Baruah, P, Marshall, JL, Nefla, M, Pucino, V, Adams, H, Turner, JD, Gilbert, S, Powell, E, Neag, G, Monksfield, P, Irving, RM, Croft, AP, Dumitriu, IE & Buckley, CD 2024, '', Frontiers in Endocrinology, vol. 15, 1397839.

Coyle, C, Ma, M, Abraham, Y, Mahony, CB, Steel, K, Simpson, C, Guerra, N, Croft, AP, Rapecki, S, Cope, A, Bowcutt, R & Perucha, E 2024, '', JCI Insight, vol. 9, no. 23, e182390.

Baruah, P, Mahony, C, Marshall, JL, Smith, CG, Monksfield, P, Irving, RI, Dumitriu, IE, Buckley, CD & Croft, AP 2024, '', British Journal of Cancer, vol. 130, no. 10, pp. 1659-1669.

Murillo-Saich, JD, Coras, R, Ramirez, J, Quesada-Masachs, E, Sala-Climent, M, Eschelbach, K, Mahony, CB, Celis, R, Armando, A, Quehenberger, O, Croft, AP, Kavanaugh, A, Chang, E, Ca帽ete, JD, Guma, M & Singh, A 2024, '', Arthritis & Rheumatology (Hoboken).

Ahmed, S, Mahony, CB, Torres, A, Murillo-Saich, J, Kemble, S, Cedeno, M, John, P, Bhatti, A, Croft, AP & Guma, M 2023, '', Arthritis Research & Therapy, vol. 25, no. 1, 176.

Khan, AO, Rodriguez-Romera, A, Reyat, JS, Olijnik, AA, Colombo, M, Wang, G, Wen, WX, Sousos, N, Murphy, LC, Grygielska, B, Perrella, G, Mahony, CB, Ling, RE, Elliott, NE, Karali, CS, Stone, AP, Kemble, S, Cutler, EA, Fielding, AK, Croft, AP, Bassett, D, Poologasundarampillai, G, Roy, A, Gooding, S, Rayes, J, Machlus, KR & Psaila, B 2023, '', Cancer Discovery, vol. 13, no. 2, pp. 364-385.

Reyat, JS, di Maio, A, Grygielska, B, Pike, J, Kemble, S, Rodriguez-Romero, A, Simoglou Karali, C, Croft, AP, Psaila, B, Sim玫es, F, Rayes, J & Khan, AO 2023, '', Frontiers in cardiovascular medicine, vol. 10.

Torres, A, Kang, S, Mahony, CB, Cede帽o, M, Oliveira, PG, Fernandez-Bustamante, M, Kemble, S, Laragione, T, Gulko, PS, Croft, AP, Sanchez-Lopez, E, Miyamoto, S & Guma, M 2023, '', Frontiers in immunology, vol. 14, 1103231.

Comment/debate

Bolton, C & Croft, AP 2024, '', Nature Reviews Rheumatology.

Hackland, A & Croft, AP 2023, '', Nature Reviews Rheumatology, vol. 19, no. 3, pp. 132-133.

Preprint

Accelerating Medicines Partnership RA/SLE Network 2025 '' bioRxiv.

Mueller, AA, Zou, AE, Marsh, L-J, Kemble, S, Nayar, S, Watts, GFM, Murphy, CL, Taylor, E, Major, T, Gardner, D, Buckley, CD, Wei, K, Raychaudhuri, S, Korsunsky, I, Filer, A, Croft, AP & Brenner, MB 2025 '' bioRxiv.

Review article

Karsdal, M, Cox, TR, Parker, AL, Willumsen, N, Sand, JMB, Jenkins, G, Hansen, HH, Oldenburger, A, Geillinger-Kaestle, KE, Larsen, AT, Black, D, Genovese, F, Eckersley, A, Heinz, A, Nystr枚m, A, Holm Nielsen, S, Bennink, L, Johannsson, L, Bay-Jensen, A-C, Orange, DE, Friedman, S, R酶pke, M, Fiore, V, Schuppan, D, Rieder, F, Simona, B, Borthwick, L, Skarsfeldt, M, Wennbo, H, Thakker, P, Stoffel, R, Clarke, GW, Kalluri, R, Ruane, D, Zannad, F, Mortensen, JH, Sinkeviciute, D, Sundberg, F, Coseno, M, Thudium, C, Croft, AP, Khanna, D, Cooreman, M, Broermann, A, Leeming, DJ, Mobasheri, A & Ricard-Blum, S 2025, '', Journal of Clinical Medicine, vol. 14, no. 6, 1856.